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Clinical Chemistry 10: 32-40, 1964;
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Clinical Chemistry, Vol 10, 32-40, Copyright © 1964 by the American Association for Clinical Chemistry

Plasma Amino Acids in Young and Older Adult Human Subjects

Philip G. Ackermann 1 and Teofil Kheim 1

1 Division of Gerontology, Washington University School of Medicine, and the St. Louis Chronic Hospital, St. Louis 39, Mo.

Nineteen amino acids were determined in the plasma of young and older individuals by the chromatographic procedure of Moore, Spackman, and Stein (7,8). Of the essential amino acids, valine, methionine, isoleucine, leucine, phenylalanine, and lysine were found to be lower in older subjects. In all, 11 of the 19 amino acids studied showed lower values in these individuals, indicating some differences in protein metabolism between the elderly and younger adults.

Submitted on March 1, 1962






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Copyright © 1964 by the American Association for Clinical Chemistry.