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Clinical Chemistry 10: 600-605, 1964;
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Clinical Chemistry, Vol 10, 600-605, Copyright © 1964 by the American Association for Clinical Chemistry

Macroglobulinemia: The Usefulness of DL-Penicillamine and Paper Electrophoresis in Diagnosis

Donald J. Campbell 1 and Thomas Boenisch 1

1 Biochemistry Division, Department of Clinical Laboratory Services, University of Alberta Hospital, Edmonton, Alberta, Canada.

The change in mobility of an abnormal globulin peak during paper electrophoresis in the presence of DL-penicillamine is the most useful of simple procedures suggested for differentiation between macroglobulin and myeloma protein. However, not all cases indicating macroglobulin by this procedure will correlate with criteria based on ultracentrifuge analysis or antigenic reaction.

Submitted on July 11, 1962







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Copyright © 1964 by the American Association for Clinical Chemistry.