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Clinical Chemistry 11: 914-919, 1965;
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Clinical Chemistry, Vol 11, 914-919, Copyright © 1965 by the American Association for Clinical Chemistry

Phenothiazine Derivatives in Urine: "False Nagative Results" With the Forrest Color Test (FPN), and a Method for Their Elimination

K. N. Campbell 1

1 Biochemistry Laboratories, Department of Clinical Research, Ontario Hospital, New Toronto, Toronto 14, Ont., Canada.

More than 100 Forrest color tests (FPN) were performed on urine specimens from patients taking phenothiazine drugs. The results obtained showed > 20% "false negatives" and 6% "false positives." A delayed reaction due to possible individual patient variation seems to have been the cause for false-negative results. These false negatives were shown to disappear when test readings were delayed for 1-5 min. Some false positives were due to liver dysfunction.

Submitted on April 28, 1965
Accepted on July 9, 1965







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Copyright © 1965 by the American Association for Clinical Chemistry.