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Clinical Chemistry 11: 943-950, 1965;
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Clinical Chemistry, Vol 11, 943-950, Copyright © 1965 by the American Association for Clinical Chemistry

Stabilization and Preservation of Serum Prostatic Acid Phosphatase Activity

Richard P. Doe 1, George T. Mellinger 1, and Ulysses S. Seal 1

1 Metabolic Research Laboratory and Urology Section, Minneapolis Veterans Administration Hospital, and the Departments of Medicine, Urology, and Biochemistry, University of Minnesota, Minneapolis, Minn.

The effects of pH and temperature of storage on the stability of the prostatic fraction of serum acid phosphatase activity have been studied in order to provide a satisfactory method for the preservation of activity in serums shipped from other hospitals. Addition of citrate tablets of a composition to buffer the serums at pH 6.2 was found to preserve the original activity at 25° for at least 7 days. These results were validated on a series of serums, subdivided into control and citrate-containing aliquots, shipped from the participating hospitals.

Submitted on May 7, 1965
Accepted on July 20, 1965




The following articles in journals at HighWire Press have cited this article:


Home page
 Clin. Chem.Home page
M. Nakanishi, K. Yoh, K. Uchida, S. Maruo, and A. Matsuoka
Improved method for measuring tartrate-resistant acid phosphatase activity in serum
Clin. Chem., February 1, 1998; 44(2): 221 - 225.
[Abstract] [Full Text] [PDF]


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Copyright © 1965 by the American Association for Clinical Chemistry.