Clinical Chemistry
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 11: 1045-1050, 1965;
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Falk, H. B.
Right arrow Articles by Kelly, R. G.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Falk, H. B.
Right arrow Articles by Kelly, R. G.

Clinical Chemistry, Vol 11, 1045-1050, Copyright © 1965 by the American Association for Clinical Chemistry

An Automated Method for the Determination of Sulfonamides in Plasma

H. B. Falk 1 and R. G. Kelly 1

1 Department of Pharmacological Research, Lederle Laboratories, American Cyanamid Company, Pearl River, N. Y. 10965.

An automated adaptation of the Bratton-Marshall procedure for sulfonamides has been developed. As sulfonamides exhibit varying degrees of protein binding, application of the method to plasma is dependent upon release of these compounds prior to automated dialysis. This release is effected by the acidification of the sample. The results obtained with and without this preliminary acidification are discussed.

Submitted on March 9, 1965
Accepted on September 7, 1965






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1965 by the American Association for Clinical Chemistry.