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Clinical Chemistry 11: 563-569, 1965;
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Clinical Chemistry, Vol 11, 563-569, Copyright © 1965 by the American Association for Clinical Chemistry

A Simple and Rapid Method for Estimating 3,4-Dihydroxyphenethylamine (Dopamine), 3,4-Dihydroxyphenylalanine (Dopa), and Homovanillic Acid (HVA) with "Two-Solutions Paper Electrophoresis"

F. Eichhorn 1 and A. Rutenberg 1

1 Rappaport Laboratories (Biochemical Section), Beilinson Hospital, Petah Tiqva, Israel.

An easy procedure for the estimation of 3,4-dihydroxyphenylalanine (dopa), 3,4-dihy-droxyphenethylamine (dopamine), and homovanillic acid (HVA), besides 3-methoxy-4-hydroxymandelic acid (VMA), by means of the "two solutions paper electrophoresis" (1) is described. Increased amounts of these phenolic compounds were found by this method in the urine of a patient with neuroblastoma, and the case report is presented.

Submitted on June 1, 1964
Accepted on August 27, 1964






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Copyright © 1965 by the American Association for Clinical Chemistry.