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Clinical Chemistry 11: 729-732, 1965;
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Clinical Chemistry, Vol 11, 729-732, Copyright © 1965 by the American Association for Clinical Chemistry

Stability of Cholinesterase in Frozen Plasma

D. G. Johnston 1 and W. C. Huff 1

1 Research Laboratory, St. John's Hospital, Oxnard, Cal.

Specimens of plasma from 51 agricultural workers were divided into several portions for freezing and storage. Periodic assays (in duplicate) for cholinesterase activity in each specimen were compared with the initial values obtained on each fresh, unfrozen specimen.

Freezing and/or thawing results in loss of approximately 30% of the plasma cholinesterase activity. It is not possible to use divided frozen portions of an initial specimen of plasma as controls for repeated testing of a subject.

Submitted on January 6, 1965
Accepted on March 1, 1965






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Copyright © 1965 by the American Association for Clinical Chemistry.