Clinical Chemistry AACC Online Job Center
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 12: 620-631, 1966;
This Article
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Seal, U. S.
Right arrow Articles by Doe, R. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Seal, U. S.
Right arrow Articles by Doe, R. P.

Clinical Chemistry, Vol 12, 620-631, Copyright © 1966 by the American Association for Clinical Chemistry

A Study of Phenyl Phosphate and alpha-Naphthyl Phospate as Substrates for SerumAcid Phosphatases

Ulysses S. Seal 1, George T. Mellinger 1, and Richard P. Doe 1

1 Metabolic Research Laboratory and Urology Section, Minneapolis Veterans Administration Hospital, and the Departments of Biochemistry, Urology, and Medicine, University of Minnesota, Minneapolis, Minn. 55417.

In 120 patients without cancer and 87 with prostatic cancer, the alpha-naphthyl phosphate substrate method proved as sensitive as or more sensitive than the tartrate inhibitable phenyl phosphate substrate method. The major nonprostatic acid phosphatase fraction of blood had properties unlike that of the red blood cell enzyme and was destroyed at room temperature, pH 6.2. Subtle local extensions of prostatic cancer were associated with small but significant increases in mean serum acid phosphatase concentration.

Submitted on April 26, 1966
Accepted on June 20, 1966






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1966 by the American Association for Clinical Chemistry.