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Clinical Chemistry 13: 220-226, 1967;
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Clinical Chemistry, Vol 13, 220-226, Copyright © 1967 by the American Association for Clinical Chemistry

A Rapid Semimicro Method for Determining Protein-Bound Iodine

Hugh Y. Yee 1, Edwin S. Katz 1, and Edward S. Jenest 1

1 Department of Pathology, Oakwood Hospital, 18101 Oakwood Blvd., Dearborn, Mich. 48124, and the Northwest Medical Laboratory, Southfield, Mich.

An improved 4 hr. semimicro method for the determination of PBI that has an S.D. of 0.30 is presented. The advantageous features include the use of a 0.1-ml. sample size, the removal of inorganic iodide by an anion resin obviating the protein-precipitation step, and the utilization of an ashing time of 35 min. The suitability of this method for the small laboratory becomes apparent in terms of the time saved as well as in the expense of equipment and reagents.

Submitted on October 4, 1966
Accepted on November 23, 1966






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Copyright © 1967 by the American Association for Clinical Chemistry.