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Clinical Chemistry 14: 1002-1009, 1968;
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Clinical Chemistry, Vol 14, 1002-1009, Copyright © 1968 by the American Association for Clinical Chemistry

Acrylamide Gel Electrophoresis of Serum Proteins in Infancy and Pregnancy

Evelyn B. Man 1 and Raymond J. Whitehead Jr. 1

1 Thyroid Laboratory of the Providence Lying-In Hospital and the Institute for Health Sciences of Brown University, Providence, R. I. 02912.

Newborns have lower concentrations of certain serum protein fractions than do those children at age 1-2 years, and significant increases in estrogen-sensitive protein fractions are recognized in pregnancy. The acrylamide-gel vertical-slab electrophoretic technic requires minimal aliquots of serum and technically is not expensive. This technic appeared potentially useful in longitudinal comparisons of increasing protein fractions during infancy and as a screening test for absence of the normal gestational increases in estrogen-sensitive protein fractions in the agr1-to agr2-globulin zone.

Submitted on January 8, 1968
Accepted on March 5, 1968






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Copyright © 1968 by the American Association for Clinical Chemistry.