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Clinical Chemistry 14: 1010-1022, 1968;
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Clinical Chemistry, Vol 14, 1010-1022, Copyright © 1968 by the American Association for Clinical Chemistry

An Automated Method for the Determination of Estrogens in Pregnancy

D. Ua Conaill 1 and G. G. Muir 1

1 Department of Biochemistry, Luton and Dunstable Hospital, Luton, Beds, Great Britain.

Ittrich’s method for the determination of total estrogens in urine (1) was adapted for automation on the AutoAnalyzer, using a continuous digester module for the combined operation of phase exchange and color development.

The automated method gave good recovery and reproducibility, and correlated well with the manual method. It increased the capacity of this laboratory for estrogen determinations, improved the turnover rate, and reduced the labor involved to a minimum.

Submitted on December 24, 1967
Accepted on June 12, 1968






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Copyright © 1968 by the American Association for Clinical Chemistry.