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Clinical Chemistry 14: 1147-1159, 1968;
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Clinical Chemistry, Vol 14, 1147-1159, Copyright © 1968 by the American Association for Clinical Chemistry

Proposals for Standardization of Total Protein Assays

Theodore Peters Jr. 1

1 The Mary Imogene Bassett Hospital (affiliated with Columbia University), Cooperstown, N. Y. 13326.

The Standards Committee of the AACC presents a discussion of the nature of total serum protein and the problems associated with its determination. Proposals are made that protein be defined as polypeptide material, and that a reference preparation be promulgated for interlaboratory use. The reference material suggested is bovine serum albumin, produced to rigid specifications and distributed as a stable 7% (w/v) solution, the concentration of which has been established by careful dry weight assay. Comments of readers are invited.




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Copyright © 1968 by the American Association for Clinical Chemistry.