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Clinical Chemistry, Vol 14, 630-636, Copyright © 1968 by the American Association for Clinical Chemistry
1 Department of Biochemistry, The Clifton Springs Hospital & Clinic, Clifton
Springs, N. Y. 14432.
An automated method is described for the determination of serum uric acid using sodium hydroxide alone as the alkalinizing agent in the uric acid-phosphotungstate reaction. Turbidity is not a problem and antiturbidity reagents are not needed. At the rate of 40 samples per hour, there is good sensitivity and good correlation with a manual urea-cyanide method. Quality control shows a standard deviation of ± 0.1 mg./100 ml.
Submitted on November 17, 1967
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