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Clinical Chemistry 15: 1039-1044, 1969;
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Clinical Chemistry, Vol 15, 1039-1044, Copyright © 1969 by the American Association for Clinical Chemistry

Analytical Bias in a Quality Control Scheme

John R. Allen 1, Rachel Earp 1, E. Christis Farrell Jr. 1, and H. D. Grümer 1

1 Division of Clinical Chemistry, Department of Pathology, The Ohio State University, Columbus, Ohio 43210.

A quality control program utilizing both "known" and "blind" control specimens was analyzed in the routine clinical chemistry laboratory. The results obtained with the control samples of 18 automated and nonautomated procedures demonstrated the presence of analytical bias. Only through the evaluation of blind control samples tested at random times can a reliable measure of the proficiency of the laboratory be achieved.

Submitted on November 29, 1968
Accepted on July 15, 1969






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Copyright © 1969 by the American Association for Clinical Chemistry.