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Clinical Chemistry 15: 271-281, 1969;
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Clinical Chemistry, Vol 15, 271-281, Copyright © 1969 by the American Association for Clinical Chemistry

Prediction of Immunoglobulins from Patterns of Cellulose Acetate Electrophoresis

M. H. Gault 1, S. Hsieh 1, and E. Elzer 1

1 Departments of Medical Chemistry and of Medicine, Queen Mary Veterans' Hospital, Montreal, Canada.

The concentrations of serum immunoglobulins (Ig) G, A, and M were correlated with specific features in the beta-ggr region of densitometer patterns of serum protein electrophoresis on cellulose acetate membranes; visual analysis of densitometer patterns permitted semiquantitative prediction of values for IgG and IgA. Important immunoglobulin abnormalities, particularly elevations of IgA, were seen in some cases even when normal values were obtained from analyses of electrophoresis by usual densitometer integrator technics; many such instances were detectable by inspection of the densitometer tracing.

Submitted on June 21, 1968
Accepted on July 25, 1968






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Copyright © 1969 by the American Association for Clinical Chemistry.