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Clinical Chemistry 15: 712-719, 1969;
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Clinical Chemistry, Vol 15, 712-719, Copyright © 1969 by the American Association for Clinical Chemistry

A Method for Measurement of Sodium and Potassium in Erythrocytes and Whole Blood

Helen I. Bugyi 1, Eugene Magnier 1, William Joseph 1, and Gordon Frank 1

1 Department of Surgery, UCLA School of Medicine, Los Angeles, Calif 90024.

The analysis of concentration of cations in erythrocytes and plasma, in theory, offers a means of identifying disease states in peripheral blood. Technical difficulties associated with cation analysis in erythrocytes and whole blood have resulted in a lack of precision and accuracy. This lack has increased the difficulties of using the analysis of blood in the diagnosis of disease. It is felt that the technic discussed in this paper with its increased precision, in combination with previously mentioned research in the diagnosis of disease, will increase the clinical significance of the analysis of red cells and whole blood for the diagnosis of disease states.

Submitted on November 19, 1968
Accepted on January 5, 1969






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Copyright © 1969 by the American Association for Clinical Chemistry.