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Clinical Chemistry 16: 118-123, 1970;
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Clinical Chemistry, Vol 16, 118-123, Copyright © 1970 by the American Association for Clinical Chemistry

Correlation between Triglycerides and Glutamic-Pyruvic Transaminase in Men on High-Fat Diets

Bernard J. Katchman 1 and Robert E. Zipf 1

1 Research Department, Miami Valley Hospital, Dayton, Ohio. Dr. Katchman’s present address is the Department of Chemistry, University of Dayton, Dayton, Ohio 45409.

Of eight young men on high-fat diets (60% of caloric intake) for 42 days, four developed serum glutamic-pyruvic transaminase concentrations greater than normal, while lactic dehydrogenase, glutamic-oxalacetic transaminase, and alkaline and acid phosphatases were within the normal range. Serum triglyceride levels were also within the normal range, but significant correlations between serum triglycerides and glutamic-pyruvic transaminase levels were found in six of the eight subjects; the mean values for all eight subjects showed a correlation significant at the 99% level of confidence. SGPT levels may be of fundamental significance along with blood triglycerides in the evaluation of fatty livers and coronary artery disease.

Submitted on March 3, 1969
Accepted on April 11, 1969




The following articles in journals at HighWire Press have cited this article:


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 ScienceHome page
S.-H. Chen and E. R. Giblett
Polymorphism of Soluble Glutamic-Pyruvic Transaminase: A New Genetic Marker in Man
Science, July 9, 1971; 173(3992): 148 - 149.
[Abstract] [PDF]


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Copyright © 1970 by the American Association for Clinical Chemistry.