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Clinical Chemistry 16: 177-179, 1970;
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Clinical Chemistry, Vol 16, 177-179, Copyright © 1970 by the American Association for Clinical Chemistry

Determination of Diazepam (Valium) Concentrations in Serum by Gas—Liquid Chromatography

Lowell B. Foster 1 and Christopher S. Frings 1

1 Medical Laboratory Associates, 1025 S. 18th St., Birmingham, Ala. 35205.

A simple, rapid, and precise gas chromatographic method for determination of serum diazepam concentrations is described. Two milliliters of serum is extracted with chloroform, and the extract is concentrated and injected into a gas chromatograph. Of the many drugs and serum samples tested, none interferes with the determination of diazepam.

Submitted on November 14, 1969
Accepted on December 22, 1969




The following articles in journals at HighWire Press have cited this article:


Home page
 ScienceHome page
E Bandman, C. Walker, and R. Strohman
Diazepam inhibits myoblast fusion and expression of muscle specific protein synthesis
Science, May 5, 1978; 200(4341): 559 - 561.
[Abstract] [PDF]


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Copyright © 1970 by the American Association for Clinical Chemistry.