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Clinical Chemistry 16: 254-255, 1970;
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Clinical Chemistry, Vol 16, 254-255, Copyright © 1970 by the American Association for Clinical Chemistry

Lactic Dehydrogenase Inhibitors in NAD

Arthur L. Babson 1 and Elsa G. Arndt 1

1 Warner-Lambert Research Institute, Morris Plains, N. J. 07950.

Commercial samples of nicotinamide adenine dinucleotide (NAD) contain various amounts of one or more lactic dehydrogenase (LDH) inhibitors but not the inhibitor described in the reduced coenzyme, NADH. The kinetic assay for LDH, in which a high concentration of NAD is used, was more seriously influenced by the source of NAD than a tetrazolium-coupled colorimetric procedure that requires much less coenzyme.

Submitted on June 25, 1969
Accepted on December 15, 1969






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Copyright © 1970 by the American Association for Clinical Chemistry.