Clinical Chemistry AACC Online Job Center
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 16: 264-268, 1970;
This Article
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Song, H.
Right arrow Articles by Tan, C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Song, H.
Right arrow Articles by Tan, C.

Clinical Chemistry, Vol 16, 264-268, Copyright © 1970 by the American Association for Clinical Chemistry

Usefulness of Serum Lipase, Esterase, and Amylase Estimation in the Diagnosis of Pancreatitis—a Comparison

Harriet Song 1, Norbert W. Tietz 1, and C. Tan 1

1 Division of Biochemistry, Mount Sinai Hospital Medical Center, Chicago, Ill. 60608, and the Chicago Medical School, University of Health Sciences.

Sera of 19 individuals with clinically established pancreatitis were analyzed for lipase activity on emulsion-type and aqueous substrates. Serum amylase concentrations were compared. Results obtained on the first and subsequent days of hospitalization clearly indicated that methods for lipase determination in which an emulsion-type substrate is used are of the greatest aid in diagnosing pancreatitis (90 to 92% of patients with pancreatitis had supranormal results). Amylase determinations were nearly as useful as an index (78% correlation), but "lipase" values obtained with methods in which aqueous substrates are used had limited clinical usefulness (29 and 32% correlation). Serum lipase elevations in cases of pancreatitis were generally greater than amylase elevations, with some exceptions. Serum lipase should be determined with a method in which emulsion-type substrates are used. Lipase and amylase values supplement one another.

Submitted on December 22, 1969
Accepted on January 22, 1970






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1970 by the American Association for Clinical Chemistry.