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Clinical Chemistry 16: 305-311, 1970;
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Clinical Chemistry, Vol 16, 305-311, Copyright © 1970 by the American Association for Clinical Chemistry

A Quality-Control Program Based on the Use of Desk-Top Digital Computer

Eugene L. Cohen 1, George Hermann III 1, and Henry T. Sugiura 1

1 Pathology Department, Presbyterian-University of Pennsylvania Medical Center, 51 N. 39th St., Philadelphia, Pa. 19104, and the University of Pennsylvania School of Medicine, Philadelphia, Pa. 19104.

Programs written for a relatively inexpensive desk-top computer are used to calculate the chemical concentration of any batch of unknowns from a flattened absorbance curve with up to five points produced by single- or dual-channel continuous-flow analyzers and other instrumentation. Any value beyond the limits of the curve is rejected. The programs are then used to evaluate a pooled control serum from previously programmed standard deviation data. The sequence of calculation is such that computation of patient samples stops if the control value lies outside these programmed limits. The system ensures that no patient sample is reported, or even calculated, unless its accompanying control was within acceptable statistical limits. Acceptance of the system by technologists has been outstanding.

Submitted on October 31, 1969
Accepted on January 8, 1970







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Copyright © 1970 by the American Association for Clinical Chemistry.