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Clinical Chemistry 16: 318-321, 1970;
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Clinical Chemistry, Vol 16, 318-321, Copyright © 1970 by the American Association for Clinical Chemistry

Simultaneous Spectrophotometric Determination of Glutethimide and Barbiturates

David W. Dain 1 and Thomas D. Trainer 1

1 Department of Pathology, College of Medicine, University of Vermont, Burlington, Vt. 05401.

A simple, rapid, quantitative method for the simultaneous analysis of barbiturates and glutethimide (2-ethyl-2-phenylglutarimide) is described. The procedure involves a single chloroform extraction from a sample buffered at pH 7.4 and requires less than an hour.

Submitted on July 8, 1969






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Copyright © 1970 by the American Association for Clinical Chemistry.