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Clinical Chemistry 16: 753-755, 1970;
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Clinical Chemistry, Vol 16, 753-755, Copyright © 1970 by the American Association for Clinical Chemistry

Automated Simultaneous Determination of p-Acetylaminohippurate and Inulin in Serum

A. Looyé 1

1 Renal Unit (Head, Dr. G. K. van der Hem), Department of Internal Medicine (Head, Prof. E. Mandema), University Hospital, Groningen, The Netherlands.

An automated determination of p-acetylaminohippurate in serum is described. It is combined with an existing procedure for determining inulin to give a simultaneous method. The same manifold can also be used to determine p-aminohippurate in combination with fructose by omitting hydrolysis. The results of automated and manual determination are compared. Recoveries of p-acetylaminohippurate and p-aminohippurate added to serum were quantitative.


Key Words: p-aminohippurate fructose • AutoAnalyzer • extended automated hydrolysis

Submitted on April 27, 1970
Accepted on May 25, 1970






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Copyright © 1970 by the American Association for Clinical Chemistry.