Clinical Chemistry Link to Randox Laboratories Web Site
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 17: 1047-1049, 1971;
This Article
Right arrow Full Text (PDF)
Right arrow A correction has been published
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Gambino, S. R.
Right arrow Articles by Fonseca, I.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Gambino, S. R.
Right arrow Articles by Fonseca, I.

Clinical Chemistry, Vol 17, 1047-1049, Copyright © 1971 by the American Association for Clinical Chemistry

Comparison of Serum Calcium Measurements Obtained with the SMA 12/60 and by Atomic Absorption Spectrophotometry

S. Raymond Gambino 1 and Ivelice Fonseca 1

1 Clinical Chemistry Laboratory, Presbyterian Hospital, 630 West 168th St., New York, N. Y. 10032.

Comparable results are obtained when serum calcium is measured by a colorimetric cresolpthalein method on the Technicon SMA 12/60 and by atomic absorption spectrophotometry (Instrumentation Laboratory Model 153 instrument), with strontium as an internal standard. Sera from 250 patients with abnormal calcium concentrations, ranging from 4.9 mg/100 ml to 9.0 mg/100 ml, were measured by each method; the difference between the means for each method was only 0.04 mg/100 ml. The standard deviation of the difference between paired results was ±0.16 mg/100 ml. We were unable to discover any effect of drug or disease on the colorimetric assay, which therefore is suitable for use in large-scale surveys. On the other hand, the more precise atomic absorption spectrophotometry is suitable for use as a reference method. In addition, with an internal standard it is fast and simple, making it suitable for emergency assays of calcium 24 h a day.


Key Words: screening and emergency uses • cresolphthalein method • Sr as internal standard

Submitted on July 5, 1971
Accepted on July 29, 1971






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1971 by the American Association for Clinical Chemistry.