Clinical Chemistry AACC Online Job Center
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 17: 122-124, 1971;
This Article
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Imashuku, S.
Right arrow Articles by LaBrosse, E. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Imashuku, S.
Right arrow Articles by LaBrosse, E. H.

Clinical Chemistry, Vol 17, 122-124, Copyright © 1971 by the American Association for Clinical Chemistry

Differentiation of Urinary N-Acetyl-p-Aminophenol from Endogenous Phenolic Compounds

Shinsaku Imashuku 1 and Elwood H. LaBrosse 1

1 Shock Trauma Unit, University of Maryland School of Medicine, Baltimore, Md. 21201.

An unknown spot, observed on two-dimensional paper chromatograms of extracts of human urine, was identified as N-acetyl-p-aminophenol (APAP), a drug metabolite. This finding suggests that APAP is clearly separable from other endogenous phenolic compounds in urine by a two-dimensional paper chromatographic method. This simple technique is feasible for the specific routine analysis of APAP in urine.


Key Words: two-dimensional paper chromatography • detection by uv absorption and chemical identification • phenacetin

Submitted on October 26, 1970
Accepted on November 18, 1970






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1971 by the American Association for Clinical Chemistry.