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Clinical Chemistry 17: 82-85, 1971;
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Clinical Chemistry, Vol 17, 82-85, Copyright © 1971 by the American Association for Clinical Chemistry

Direct Blood-Injection Method for Gas Chromatographic Determination of Alcohols and Other Volatile Compounds

Naresh C. Jain 1

1 Department of Toxicology, Indiana University Medical Center, Indianapolis, Ind. 46202.

An extremely simple, rapid method is described for simultaneously determining methanol, ethanol, acetone, isopropanol, and low-boiling hydrocarbons associated with glue sniffing. Less than 1 µl of blood, mixed with an internal standard, is injected directly into a low-cost gas chromatograph equipped with a flame-ionization detector. No extraction, distillation, and (or) sample preparation is required, and the method is sensitive to less than 10 µg of alcohol per ml.


Key Words: glue sniffing • screening of blood samples for alcohol

Accepted on October 29, 1970




The following articles in journals at HighWire Press have cited this article:


Home page
 Clin. Chem.Home page
A. Tangerman
Highly sensitive gas chromatographic analysis of ethanol in whole blood, serum, urine, and fecal supernatants by the direct injection method
Clin. Chem., June 1, 1997; 43(6): 1003 - 1009.
[Abstract] [Full Text] [PDF]


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Copyright © 1971 by the American Association for Clinical Chemistry.