Clinical Chemistry Link to Randox Laboratories Web Site
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 17: 174-182, 1971;
This Article
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lee, N. D.
Right arrow Articles by Pileggi, V. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lee, N. D.
Right arrow Articles by Pileggi, V. J.

Clinical Chemistry, Vol 17, 174-182, Copyright © 1971 by the American Association for Clinical Chemistry

Comparison of Laboratory Test Results for Assessing Thyroid Function in Normal Subjects and Treated and Untreated Hyper- and Hypothyroid Patients

Norman D. Lee 1, Boris Catz 1, M. S. Margolese 1, and Vincent J. Pileggi 1

1 Bio-Science Laboratories, 7600 Tyrone Ave., Van Nuys, Calif. 91405 (N.D.L., V.J.P.); 435 North Roxbury Dr., Beverly Hills, Calif. 90210 (B.C.); and 2080 Century Park East, Los Angeles, Calif. 90067 (M.S.M.).

Various indexes of thyroid status were measured in sera from normal men and women, normal women who were using oral contraceptives, hyper- and hypothyroid patients, and hypothyroid patients being successfully managed with various forms of replacement therapy. Total circulating thyroxine concentrations were measured by three methods as well as the thyroxine-binding capacity of the serum inter-alpha globulin, "free" thyroxine, and "free" thyroxine index. Our purpose was to compare the various measurements, and to assess their diagnostic usefulness. The most significant finding was that, of 197 hypothyroid patients, all of whom possessed total circulating thyroxine concentrations within normal limits, 28% showed subnormal "free" thyroxine concentrations.


Key Words: normal ranges • "free" and "bound" serum thyroxine • effects of oral contraceptive medications • "nonclassic" hypothyroidism • diagnostic aids

Submitted on October 7, 1970
Accepted on December 29, 1970






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1971 by the American Association for Clinical Chemistry.