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Clinical Chemistry 17: 316-320, 1971;
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Clinical Chemistry, Vol 17, 316-320, Copyright © 1971 by the American Association for Clinical Chemistry

Urinary Estrogen Determination in Pregnancy

A. T. Howarth 1 and D. M. Robertshaw 1

1 Biochemistry Department, The Royal Infirmary, Bradford 9, Yorkshire, England.

Results of an extensive trial of a quick fluorometric determination of estriol in pregnancy urine are described. The method is compared with the much more laborious one of Oakey et al. [Clin. Chim. Acta 15, 35 (1967)]. Trial of another apparently simpler method indicated it to be unsatisfactory in practice. The method described is accurate, simple, and rapid.


Key Words: intercomparison of methods • fluorometry • interference by glucose • fetal malfunction

Submitted on October 28, 1970
Accepted on January 21, 1971






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Copyright © 1971 by the American Association for Clinical Chemistry.