Clinical Chemistry AACC Online Job Center
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 17: 833-840, 1971;
This Article
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Zief, M.
Right arrow Articles by Michelotti, F. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Zief, M.
Right arrow Articles by Michelotti, F. W.

Clinical Chemistry, Vol 17, 833-840, Copyright © 1971 by the American Association for Clinical Chemistry

Clinical Chemistry: A Challenge for High-Purity Standards and Reagents

M. Zief 1 and F. W. Michelotti 1

1 Research Laboratory, J. T. Baker Chemical Co., Phillipsburg, N. J. 08865.

The dynamic interplay between preparation, handling, containment, and analysis of ultrapure chemical standards and reagents for the clinical chemistry laboratory is described. Inorganic as well as organic standards are reviewed. The contamination problems associated with water, acids, and solvents in trace-element analysis are defined and resolved. In addition, less well-known sources of error in trace analysis are reviewed, as are the common contaminants in the clinical laboratory. It does little good to use a 99.99% primary standard with water of unknown quality in a heavily contaminated laboratory. Fortunately, recognition, definition, and solution of this problem is possible and should introduce new levels of precision and accuracy in the clinical chemistry laboratory.


Key Words: sources of contamination, positive and negative • preparation of high-purity standards, organic ond inorganic • trace analysis






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1971 by the American Association for Clinical Chemistry.