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Clinical Chemistry 18: 48-51, 1972;
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Clinical Chemistry, Vol 18, 48-51, Copyright © 1972 by the American Association for Clinical Chemistry

Determination of SMA—Mark X1,2 Set Points for Bilirubin by Standard Addition Technique

Ronald H. Laessig 1, Thomas H. Schwartz 1, and Thomas A. Paskey 1

1 State Laboratory of Hygiene, University of Wisconsin, Madison, Wis. 53706.

A technique based on the standard addition method is described for calibration of the bilirubin channel on the SMA and Mark X analytical systems. Reference sera used for set point calibration contain significant blanks that are compensated in the present technique, which is based on actual bilirubin response of the respective instruments. Precision is improved by use of a least squares technique.


Key Words: bilirubin calibration • least squares • automated multi-channel analytical systems

Submitted on August 12, 1971






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Copyright © 1972 by the American Association for Clinical Chemistry.