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Clinical Chemistry, Vol 18, 1463-1467, Copyright © 1972 by the American Association for Clinical Chemistry
1 Departments of Medicine and Biochemistry, Louisiana State University School of Medicine, New Orleans, La. 70112.
A simplified primary screening procedure is described for determining serum
- plus pre-
-lipoproteins, which is more rapid and less expensive than
cholesterol or triglyceride determinations. This method is based on the ability of
- and pre-
-lipoproteins to form insoluble complexes with heparin in
presence of Ca2+. Comparison with analytical ultracentrifugation indicated the accuracy of concentrations determined by the present method. This method was used to screen a group of healthy adults and
children and diabetic patients. The results show that
measuring serum
- plus pre-
-lipoprotein concentrations may be more useful for screening and detecting subtle abnormalities than is determination of
either cholesterol or triglyceride.
- plus pre-
-lipoprotein index analytical ultracentrifugation diabetes screening heparin
complex LDL VLDL
Submitted on July 17, 1972
Accepted on August 31, 1972
The following articles in journals at HighWire Press have cited this article:
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J. L. Cresanta, S. R. Srinivasan, L. S. Webber, and G. S. Berenson Serum Lipid and Lipoprotein Cholesterol Grids for Cardiovascular Risk Screening of Children Arch Pediatr Adolesc Med, April 1, 1984; 138(4): 379 - 387. [Abstract] [PDF] |
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