Clinical Chemistry
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 18: 1463-1467, 1972;
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Berenson, G. S.
Right arrow Articles by Dalferes, E. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Berenson, G. S.
Right arrow Articles by Dalferes, E. R., Jr.

Clinical Chemistry, Vol 18, 1463-1467, Copyright © 1972 by the American Association for Clinical Chemistry

Simplified Primary Screening Procedure for Detection of Hyperlipidemias in Healthy Individuals

Gerald S. Berenson 1, S. R. Srinivasan 1, P. S. Pargaonkar 1, B. Radhakrishnamurthy 1, and Edward R. Dalferes Jr. 1

1 Departments of Medicine and Biochemistry, Louisiana State University School of Medicine, New Orleans, La. 70112.

A simplified primary screening procedure is described for determining serum beta- plus pre-beta-lipoproteins, which is more rapid and less expensive than cholesterol or triglyceride determinations. This method is based on the ability of beta- and pre-beta-lipoproteins to form insoluble complexes with heparin in presence of Ca2+. Comparison with analytical ultracentrifugation indicated the accuracy of concentrations determined by the present method. This method was used to screen a group of healthy adults and children and diabetic patients. The results show that measuring serum beta- plus pre-beta-lipoprotein concentrations may be more useful for screening and detecting subtle abnormalities than is determination of either cholesterol or triglyceride.


Key Words: serum beta- plus pre-beta-lipoprotein index • analytical ultracentrifugation • diabetes • screening • heparin complex • LDL • VLDL

Submitted on July 17, 1972
Accepted on August 31, 1972




The following articles in journals at HighWire Press have cited this article:


Home page
 Arch Pediatr Adolesc MedHome page
J. L. Cresanta, S. R. Srinivasan, L. S. Webber, and G. S. Berenson
Serum Lipid and Lipoprotein Cholesterol Grids for Cardiovascular Risk Screening of Children
Arch Pediatr Adolesc Med, April 1, 1984; 138(4): 379 - 387.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1972 by the American Association for Clinical Chemistry.