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Clinical Chemistry 18: 129-130, 1972;
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Clinical Chemistry, Vol 18, 129-130, Copyright © 1972 by the American Association for Clinical Chemistry

Gas-Chromatographic Determination of Total Estriol in Amniotic Fluid

Joseph C. Touchstone 1, Taras Murawec 1, and Ronald J. Bolognese 1

1 Steroid Laboratory, Departments of Obstetrics and Gynecology, and Harrison Department of Surgical Research, School of Medicine, University of Pennsylvania; and Pennsylvania Hospital, Philadelphia, Pa. 19104.

A simple gas-chromatographic procedure is described for determination of total estriol in amniotic fluid. Before 20 weeks gestation the concentrations (<1 µg/100 ml) were not meaningful. After 20 weeks there was a gradual rise, followed by a rapid rise during the last weeks of pregnancy.

Submitted on August 4, 1971
Accepted on October 22, 1971






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Copyright © 1972 by the American Association for Clinical Chemistry.