Clinical Chemistry
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Clinical Chemistry 18: 340-348, 1972;
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Clinical Chemistry, Vol 18, 340-348, Copyright © 1972 by the American Association for Clinical Chemistry

Comparison of Results from the Du Pont "ACA" and Technicon "SMA 12/ 60"

James O. Westgard 1 and Brenda L. Lahmeyer 1

1 Medicine and the Clinical Laboratories, University of Wisconsin Center for Health Sciences, Madison, Wis. 53706.

The Du Pont "Automatic Clinical Analyzer" (ACA) and the Technicon "SMA 12/60" were compared as to precision, range of linearity, and results for sera from patients. Precision of the ACA was equal to or better than that of the SMA 12/60 for all determinations except SGOT in the normal range. The ACA showed a wider range of linearity for BUN, total protein, LDH, alkaline phosphatase, SGOT, and bilirubin, and equal linear ranges for glucose and albumin. Patient’s sera comparisons showed differences for glucose in uremic sera. Albumin values from the ACA did not compare well with those by HABA dye method from the SMA 12/60, but did compare well with values obtained by electrophoresis and by a bromcresol green method adapted to the SMA 12/60. Bilirubin values from the ACA were higher than those from the SMA 12/60. Comparable results were obtained for the enzyme determinations when the SMA 12/60 was calibrated in the same units as the ACA.


Key Words: clinical laboratory values • performance of automated systems compared • ESKALAB • glucose in uremic serum • electrophoresis on cellulose acetate • precision of secondary analytical methods • AutoAnalyzer • DSA 560 • emergency service

Submitted on November 11, 1971
Accepted on January 3, 1972






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Copyright © 1972 by the American Association for Clinical Chemistry.