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Clinical Chemistry 18: 405-409, 1972;
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Clinical Chemistry, Vol 18, 405-409, Copyright © 1972 by the American Association for Clinical Chemistry

Rapid Identification of Psychopharmacologic Agents in Cases of Drug Abuse

David Sohn 1 and Julius Simon 1

1 New York Medical College, Center for Chronic Disease, Bird S. Coler Hospital, Welfare Island, New York, N. Y. 10017 (D. S.); and the Laboratory for Chromatography, 212-14 48th Ave., Bayside, N. Y. 11364 (J. S.). Address reprint requests to J.S.

When a patient is hospitalized in coma with suspected drug overdose, rapid identification of psychopharmacologic or toxic agents is essential. Methods for excluding other common toxic agents are indicated. Psychomimetic drugs that should be identified are enumerated. Screening by thin-layer chromatography is suggested as the method of choice, with confirmation or quantification by gas chromatography. Appropriate references to current methodology are appended.


Key Words: gas—liquid chromatography • thin-layer chromatography • toxicology • emergency diagnosis

Submitted on July 5, 1971
Accepted on December 28, 1971






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Copyright © 1972 by the American Association for Clinical Chemistry.