Clinical Chemistry Link to Randox Laboratories Web Site
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 18: 613-615, 1972;
This Article
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Helson, L.
Right arrow Articles by Schwartz, M. K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Helson, L.
Right arrow Articles by Schwartz, M. K.

Clinical Chemistry, Vol 18, 613-615, Copyright © 1972 by the American Association for Clinical Chemistry

Urinary Cystathionine, Catecholamine, and Metabolites in Patients with Neuroblastoma

L. Helson 1, M. Fleisher 1, V. Bethune 1, M. L. Murphy 1, and M. K. Schwartz 1

1 Departments of Pediatrics and Biochemistry, Memorial Hospital for Cancer and Allied Diseases, New York, N.Y. 10021.

Urinary excretions of cystathionine, catecholamines, and vanillymandelic acid were compared in 27 patients with neuroblastoma and in nine other patients with non-neurogenic tumors. Eleven of the 27 patients were without clinical evidence of active neuroblastoma at the time of the study and excreted no or relatively small amounts of urinary cystathionine. Thirteen of the remaining 16 patients with progressive neuroblastoma had elevated cystathionine values. Elevated values were also detected in three of nine patients with other tumors. There was no correlation between the excretion of cystathionine and either catecholamines or vanillymandelic acid. The assay of cystathionine in addition to catecholamines and vanillymandelic acid is recommended for the complete biochemical evaluation of patients with neuroblastoma.


Key Words: interrelations of changes in excretion • diagnostic index • vanillylmandelic acid

Submitted on March 13, 1972
Accepted on April 17, 1972






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1972 by the American Association for Clinical Chemistry.