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Clinical Chemistry 18: 643-646, 1972;
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Clinical Chemistry, Vol 18, 643-646, Copyright © 1972 by the American Association for Clinical Chemistry

Rapid Gas Chromatographic Measurement of Plasma Procainamide Concentration

Arthur J. Atkinson Jr. 1, Michele Parker 1, and John Strong 1

1 Clinical Pharmacology Laboratory, Division of Medicine, Passavant Memorial Hospital, 303 E. Superior St., Chicago, Ill. 60611; and the Departments of Medicine and Pharmacology, Northwestern University Medical School, Chicago, Ill. 60611.

A gas-chromatographic method has been developed for measuring procainamide in plasma. This simple analysis can be performed in less than an hour with a standard deviation of less than 8% for concentrations of procainamide in the range that is commonly encountered in clinical practice (1-20 mg/liter).


Key Words: Pronestyl • ventricular arrhythmias

Submitted on April 4, 1972
Accepted on May 3, 1972






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Copyright © 1972 by the American Association for Clinical Chemistry.