Clinical Chemistry
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Clinical Chemistry 18: 1013-1018, 1972;
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Clinical Chemistry, Vol 18, 1013-1018, Copyright © 1972 by the American Association for Clinical Chemistry

Development and Evaluation of a High-Speed Continuous-Flow Analyzer

M. A. Evenson 1 and M. A. Olson 1

1 Department of Medicine and Clinical Chemistry Laboratory, University of Wisconsin, Madison, Wis. 53706.

A high-speed, high-performance, continuous-flow analyzer is described that operates at two to three times the usual analysis rate without necessitating corrections of the raw data and with no decrease in accuracy or precision. At faster speeds (180-300 samples/h) inductive sample interaction (%Ii), opposite in direction to carry-over, is for the first time quantitatively measured. A correction equation for %Ii was developed, and when it is applied to raw data, the accuracy of the results are significantly improved. Operating characteristics of the high-speed analyzer are described and the desirability of automatic computer corrections is discussed for the high-speed system.


Key Words: AutoAnalyzers • glucose • blood urea nitrogen • creatinine • correlation • statistical evaluation of methods • accuracy • precision • "inductive sample interaction" • carry-over sample interaction

Submitted on May 15, 1972
Accepted on July 6, 1972






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Copyright © 1972 by the American Association for Clinical Chemistry.