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Clinical Chemistry 18: 909-910, 1972;
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Clinical Chemistry, Vol 18, 909-910, Copyright © 1972 by the American Association for Clinical Chemistry

Comparison of Manometric and Infrared Methods for Determining Carbon Monoxide in Blood

Loren G. Myhre 1

1 Department of Physiology, Lovelace Foundation for Medical Research, 5200 Gibson Blvd., S.E., Albuquerque, N. Mex. 87108.

Twelve samples of blood containing carbon monoxide (CO) ranging from 0.24 to 6.80 vol % were analyzed in duplicate by a manometric method and by two other methods in which an infrared CO meter is used. The analytical precision was within ±0.015 vol % for all methods, and the differences observed in blood CO between any two methods were not statistically significant. One of the methods with the infrared CO meter was preferred because, without sacrificing either precision or accuracy, it was considerably more convenient and technically less demanding than either of the other methods.

Submitted on April 27, 1972
Accepted on May 22, 1972






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Copyright © 1972 by the American Association for Clinical Chemistry.