Clinical Chemistry
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Clinical Chemistry 19: 123-124, 1973;
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Clinical Chemistry, Vol 19, 123-124, Copyright © 1973 by the American Association for Clinical Chemistry

Anomalous Response of Macroamylase to Assay Temperature

Arthur R. Henderson 1, John King 1, and Clement W. Imrie 1

1 From the University Department of Pathological Biochemistry, Department of Biochemistry and Division of Surgery, Glasgow Royal Infirmary, Glasgow, Scotland, G4 OSF.

An anomalous response to increased reaction temperature is described for two samples of macroamylase, as contrasted with normal serum and pancreatic amylases. A possible method of differentiating macroamylase by assays of activities at 45°C and 25°C is suggested. The ratios of activities found at these two temperatures for a normoamylasemic population are given


Key Words: macroamylasemia • normal values • acute pancreatitis • diagnostic aid • bound and free enzyme

Submitted on July 26, 1972
Accepted on October 26, 1972






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Copyright © 1973 by the American Association for Clinical Chemistry.