Clinical Chemistry
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Clinical Chemistry 19: 1387-1389, 1973;
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Clinical Chemistry, Vol 19, 1387-1389, Copyright © 1973 by the American Association for Clinical Chemistry

Comparison of Diagnostic Accuracy of agr-Hydroxybutyrate Dehydrogenase Assays by Two Spectrophotometric Procedures

Richard J. Spooner 1 and David M. Goldberg 1

1 Department of Chemical Pathology, Royal Hospital, West St., Sheffield S1 3SR, England.

agr-Hydroxybutyrate dehydrogenase activity was measured in 66 sera from cases of myocardial infarction and 91 sera from cases of hepatobiliary disease by the original procedure at 25 °C [Nature 188, 1110 (1960)] and the revised procedure at 37 °C [Amer. J. Clin. Pathol. 56, 627 (1971)]. The diagnostic accuracy of the two procedures was comparable, but the superior precision of the revised procedure makes it more suitable as a laboratory routine.

Submitted on June 27, 1973






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Copyright © 1973 by the American Association for Clinical Chemistry.