Clinical Chemistry
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Clinical Chemistry 19: 1389-1391, 1973;
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Clinical Chemistry, Vol 19, 1389-1391, Copyright © 1973 by the American Association for Clinical Chemistry

Coupling of Glucose-6-Phosphate Dehydrogenase and Hemoglobin S Screening to Automated Determinations of Blood Group and Type

John S. Maples 1, Larry G. Dickson 1, and David E. Uddin 1

1 Naval Hospital, Great Lakes, Ill. 60088 (J.S.M.); and the Naval Medical Research Institute, National Naval Medical Center, Bethesda, Md. 20014.

Automated analyses for glucose-6-phosphate dehydrogenase (EC 1.1.1.49, GPD) and for hemoglobin S have recently been described. We modified these methods to couple them directly to the sample line of the 15-channel Technicon blood-typing analyzer. Rate of analysis is doubled (to 120 per hour) by using the reverse-washout cycle to decrease sample-to-sample interaction. Savings in reagents and technician time are significant.


Key Words: AutoAnalyzer • population screening

Submitted on August 25, 1973






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Copyright © 1973 by the American Association for Clinical Chemistry.