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Clinical Chemistry, Vol 19, 366-372, Copyright © 1973 by the American Association for Clinical Chemistry
I discuss pitfalls in laboratory-screening programs: regression toward the mean on repeated biochemical determinations; the problem of defining normalcy in the interpretation of laboratory test results; and a remarkable professional myopia in which clinical chemists have, with rare exception, failed to accept responsibility for evaluating whether the programs in which they are engaged are of benefit to patients.
Accepted on January 10, 1973
The following articles in journals at HighWire Press have cited this article:
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R. D. CEBUL and J. R. BECK Diagnostic Decision: Biochemical Profiles * Applications in Ambulatory Screening and Preadmission Testing of Adults Ann Intern Med, March 1, 1987; 106(3): 403 - 413. [Abstract] [PDF] |
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C. C. KORVIN, R. H. PEARCE, and J. STANLEY Admissions Screening: Clinical Benefits Ann Intern Med, August 1, 1975; 83(2): 197 - 203. [Abstract] [PDF] |
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J. C. BOYD and J. J. MARR Decreasing Reliability of Acid-Fast Smear Techniques for Detection of Tuberculosis Ann Intern Med, April 1, 1975; 82(4): 489 - 492. [Abstract] [PDF] |
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