Clinical Chemistry AACC Online Job Center
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Clinical Chemistry 19: 390-394, 1973;
This Article
Right arrow Full Text (PDF)
Right arrow Submit an electronic Letter to
the Editor about this paper
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hayes, T. S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hayes, T. S.

Clinical Chemistry, Vol 19, 390-394, Copyright © 1973 by the American Association for Clinical Chemistry

Automated Fluorometric Determination of Amphetaminein Urine

T. S. Hayes 1

1 Department of Pharmaceutical Chemistry, University of Strathclyde, Glasgow, Scotland.

A completely automated fluorometric determination of amphetamine in urine is described and evaluated. The dihydrolutidine derivative produced by reaction of amphetamine with formaldehyde and acetylacetone is excited at 410 nm and the resulting intensity of fluorescence measured at 476 nm. The working limit of detection of amphetamine in fresh urine (1.5-ml samples) is 0.15 mg/liter. A result is produced for the first sample in about 20 min; subsequent results are obtained at 2-min intervals. Falsely positive reactions are given by 2-phenylethylamine and tuaminoheptane.


Key Words: dihydrolutidine derivative • AutoAnalyzer

Submitted on December 1, 1972
Accepted on January 8, 1973






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1973 by the American Association for Clinical Chemistry.