Clinical Chemistry
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Clinical Chemistry 19: 463-465, 1973;
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Clinical Chemistry, Vol 19, 463-465, Copyright © 1973 by the American Association for Clinical Chemistry

Rapid Method for Screening for Galactosemia and Galactokinase Deficiency by Measuring Galactose in Whole Blood Spotted on Paper

André Grenier 1 and Claude Laberge 1

1 From the Division of Human Genetics, Centre Hospitalier de l’Université Laval, Québec-10, Québec, Canada.

An inexpensive automated fluorometric technique for blood galactose determination has been modified to use dried blood spots available through phenylketonuria screening programs. The method is more efficient because of its high capacity (sime85,000 tests a year), low cost (sime$3,000 a year in reagents), and high specificity (enzymatic method).


Key Words: AutoAnalyzer • mass screening • disorders of galactose metabolism • fluorometry

Submitted on December 30, 1972
Accepted on February 12, 1973




The following articles in journals at HighWire Press have cited this article:


Home page
 Arch Pediatr Adolesc MedHome page
M. H. LIPSON and P. J. Russo
Normal Initial Blood Galactose Levels in a Newborn With Galactosemia
Arch Pediatr Adolesc Med, August 1, 1982; 136(8): 747 - 748.
[Abstract] [PDF]


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Copyright © 1973 by the American Association for Clinical Chemistry.