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Clinical Chemistry 19: 998-1001, 1973;
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Clinical Chemistry, Vol 19, 998-1001, Copyright © 1973 by the American Association for Clinical Chemistry

Liquid-Scintillation Counting of [57Co]—Application to the Radioassay of Vitamin B12

Sidney Gutcho 1, James Johnson 1, and Henry McCarter 1

1 Schwarz/Mann, Division of Becton, Dickinson and Co., Orangeburg, N. Y. 10962.

Cobalt-57 can be measured in a liquid scintillation counting system. We describe the calibration of such a system for this gamma emitter. The counting procedure has been used in the radioassay of vitamin B12. Results of assays for which counting of bound radioisotope was done in a gamma scintillation spectrometer and in a liquid scintillation counter show that either counting system can be used for the measurement of [57Co].


Key Words: counting of gamma emitters • radiolabeled vitamin B12 • diagnosis of the anemias

Submitted on May 17, 1973
Accepted on June 5, 1973






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Copyright © 1973 by the American Association for Clinical Chemistry.