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Clinical Chemistry 20: 41-42, 1974;
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Clinical Chemistry, Vol 20, 41-42, Copyright © 1974 by the American Association for Clinical Chemistry

CEA-Like Material in Fluid from Benign Cysts of the Breast

Martin Fleisher 1, Herbert F. Oettgen 1, Charles N. Breed 1, Guy F. Robbins 1, Carl M. Pinsky 1, and Morton K. Schwartz 1

1 Memorial Sloan-Kettering Cancer Center, New York, N. Y.

A preliminary survey of carcinoembryonic antigen (CEA) concentrations in 23 breast-cyst fluids (BCF) and blood plasma has revealed markedly increased concentrations of CEA-like material in BCF as compared to its concentrations in plasma. Chromatography on Sephadex G-200 indicated the immunoreactive CEA component extracted from BCF corresponds to a glycoprotein with a molecular weight of at least 200 000.


Key Words: Sephadex chromatography

Accepted on October 29, 1973






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Copyright © 1974 by the American Association for Clinical Chemistry.