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Clinical Chemistry 20: 1499-1506, 1974;
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Clinical Chemistry, Vol 20, 1499-1506, Copyright © 1974 by the American Association for Clinical Chemistry

Calculations and Correction Factors Used in Determination of Blood pH and Blood Gases

Robert W. Burnett 1 and Daniel C. Noonan 1

1 Clinical Chemistry Laboratory, Hartford Hospital, Hartford, Conn. 06115.

Measurement of blood pH, po2 and pco2 also involves calculation of two or more derived quantities and correction of the measured values in cases where the body temperature of the patient differs from the temperature of measurement. References to the pertinent calculations and the temperature corrections are scattered through the literature of several medical specialties, and much new information has been gathered in recent years that directly affects these calculations. This review explains each of the derived quantities and correction factors most used in this field and also provides the best available data for the calculations, in a form that can readily be adapted to electronic data processing.


Key Words: po2 • pco2 • CO2 content • plasma bicarbonate concentration • base excess • oxyhemoglobin dissociation curve • O2 saturation • O2 content • temperature corrections

Submitted on August 6, 1974




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Copyright © 1974 by the American Association for Clinical Chemistry.