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Clinical Chemistry 20: 1578-1579, 1974;
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Clinical Chemistry, Vol 20, 1578-1579, Copyright © 1974 by the American Association for Clinical Chemistry

Transport of Beta-Carotene in Serum of Individuals with Carotenemia

Micheline M. Mathews-Roth 1 and Christian L. Gulbrandsen 1

1 Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Mass.; the Channing Laboratory, Boston City Hospital, 774 Albany St., Boston, Mass. 02118; and the Department of Medicine, University of Hawaii School of Medicine, Honolulu, Hawaii.

We studied distribution of carotene in the various serum lipid fractions of carotenemic and noncarotenemic individuals. We found that the amount of carotene in each lipoprotein fraction is increased in the serum from carotenemic individuals, but that the relative increase is significant only in the low-density lipoprotein and high-density lipoprotein fractions. There was no significant difference between the cholesterol concentrations of each fraction of the carotenemic individuals' and noncarotenemic individuals' sera, indicating that serum betalipoprotein is not increased in carotenemia.

Submitted on August 7, 1974




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Copyright © 1974 by the American Association for Clinical Chemistry.