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Clinical Chemistry, Vol 20, 266-271, Copyright © 1974 by the American Association for Clinical Chemistry
1 Merck Institute for Therapeutic Research, Rahway, N. J.
07065, and the Merck Institute for Therapeutic Research, West
Point, Pa. 19486.
We describe a radioimmunoassay for detection of dexamethasone in plasma. Antibodies to dexamethasone hemisuccinate coupled to bovine serum albumin were obtained in rabbits and used for binding of the synthetic steroid. Concentrations of dexamethasone between 0.5 and 40 µg/liter of plasma can be measured with this procedure.
Submitted on July 6, 1973
Accepted on November 28, 1973
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