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Clinical Chemistry 20: 499-501, 1974;
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Clinical Chemistry, Vol 20, 499-501, Copyright © 1974 by the American Association for Clinical Chemistry

Mechanism of Interference by Uric Acid in the Glucose Oxidase/Peroxidase Method for Serum Glucose

Nguyen H. Chinh 1

1 Department of Pathology, Piedmont Hospital, 1968 Peachtree St., N.W., Atlanta, Ga. 30309.

Uric acid lowers the value for glucose as determined by the "GOD-Perid" method. To localize the interference by uric acid, we investigated each step of the reaction. Bleaching of the final color is the only source of such interference.


Key Words: "kit" method

Submitted on November 30, 1973
Accepted on January 12, 1974






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Copyright © 1974 by the American Association for Clinical Chemistry.